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The San Francisco 49ers quarterback Brock Purdy went on a journey from "Mr. Irrelevant" to football superstar.

Homeland Security Secretary Alejandro Mayorkas testified Tuesday before Republican lawmakers who threatened to impeach him. Immigrant advocates race to pass what they can during the lame duck.

Top Illinois lawmakers say they'd like to call the legislature into session for a special election to pick President-elect Barack Obama's Senate replacement. They don't want to leave that job to Gov. Rod Blagojevich who's accused by federal prosecutors of trying to sell the seat. The governor and the president-elect are not personally close, but they have worked closely together over the years.

In talks to frame an Iraqi constitution, a top Shiite political leader calls for autonomy for the Shiite-dominated region of southern Iraq. In the north, Kurdish leaders made similar demands. Iraq's Shiite prime minister rejected the proposals.

Most of the largest pharmaceutical companies report losing money in the United States, despite the majority of their sales coming from Americans. The result is lower U.S. taxes for the companies.

The militia fired dozens of rockets at northern Israel, warning that the barrage was its initial response to the targeted killing of a top leader from the allied Hamas group in Lebanon's capital.

In Michigan, unions have bet big on ballot proposals to stem a tide of Republican legislation curtailing organized labor's ability to bargain contracts, collect dues, and raise money for political races. Their top goal is to make sure the state legislature cannot pass a so-called right-to-work law that outlaws compulsory union membership. They also want to reverse a law that allows the state to temporarily take over financially struggling local governments and scrap public employee contracts.

Sky-high gas prices have drivers going out of their way for discounts at the pump. Oil executives warn that even higher prices might be on the horizon.

Trump's national security strategy, which seeks to "restore American preeminence in the Western Hemisphere."

On Sunday, the selection committee set the field for the annual descent into March Madness. The four No. 1 seeds are defending champion Villanova, North Carolina, Kansas and Gonzaga.