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An official assessment by Gen. Stanley McChrystal, the top U.S. commander in Afghanistan, concludes that after eight years, the U.S. and its allies have failed to focus on and win over the Afghan people. He also calls for more troops to ensure victory over the Taliban and al-Qaida.

The latest film in the space odyssey juggernaut brought in $450 million globally in its debut weekend, and that's not counting China.

A growing number of start-ups are offering at-home tests that let you check your thyroid, your fertility, even food sensitivities. But some doctors view the tests with skepticism.

Facebook's new chief lawyer is tasked with guiding the firm through increasingly treacherous legal woes. Jennifer Newstead was one of the lawyers who crafted the controversial Patriot Act.

The Oscar-nominated Kokuho tells a compelling story about friendship, the weight of history and the torturous road to becoming a star in Japan's Kabuki theater.

Some 1.1 million people are living with HIV in the United States, according to new figures from the Centers for Disease Control and Prevention. In a survey of Baltimore, Los Angeles, Miami, New York City and San Francisco in the past year, 46 percent of the black men surveyed at local bars and dance clubs were HIV positive.

President Bush arrives at the G-8 summit in Germany on Wednesday with a new plan on climate change as leaders of major industrialized countries gather for three days. But a bitter debate over missile defense looms over the talks.

Since 2008, Bella has been the city's most popular dog name. That's when the last of Stephenie Meyer's vampire-themed Twilight novels featuring heroine Bella Swan was published.

Republicans are feeling pressure to deliver the first overhaul of the federal tax code in more than 30 years after the collapse of the long-promised dismantling of the Affordable Care Act.

State law lets any member of the bar be appointed as a public defender. Gov. Jay Nixon was assigned a client, but Nixon's spokesman says you can't appoint an attorney without the attorney's consent.